The University of Michigan School of Public Health
Zellers LabIntegrated Environmental Microsystems

Zellers Lab - Integrated Environmental Microsystems

   Leader      Edward T. Zellers, Ph.D.
   Major field      Exposure
Keywords
Exposure Science, Exposure Technology, air monitoring, biological monitoring, direct-reading instruments, sampling strategies, exposure modeling, Lab-On-A-Chip, Micro Gas Chromatography, Micro Instrumentation, Integrated Environmental Microsystems; Microsensor Arrays; Microanalytical, ; Chemometrics, VOCs, Complex Mixtures; Industrial Hygiene, Environmental Monitoring, Biomarkers, Homeland Security, Separations, Preconcentration, Detection, MEMS
Integrated Environmental Microsystems
Description

The assessment of human exposure to complex mixtures of natural and anthropogenic chemicals ranks among the most important global environmental health challenges. Our ability to meet evolving needs in this area relies critically on innovations in exposure science and technology. Advances that facilitate accurate, high-resolution measurements are integral to mankind's efforts to unravel the intricate relationships between exposure and the risks of adverse health effects, and to minimize such risks.


Professor Zellers' research and teaching interests lies at the intersection of Environmental Health Science, Chemistry, and Engineering. His work deals with the fundamental and applied aspects of exposure science and technology and contributes to the broad goal of developing the means to quantitatively analyze complex chemical mixtures of arbitrary composition in field settings.

Research Areas

bulletMicrosensors and Microsensor Arrays.

In the area of chemical microsensors, Dr. Zellers' focus has evolved from a primary focus on microsensors that utilize surface-acoustic-wave (SAW) propagation through small piezoelectric substrates to a broader set of transduction platforms, including film-bulk-acoustic-resonators, chemiresistors, capacitors, cantilevers, calorimeters, and multi-transducer arrays employing combinations of such devices... >> more

bulletLab On A Chip.

Increasing evidence suggests that the number of vapors that can be simultaneously recognized and differentiated with standalone sensor arrays is limited and that quantitative analyses of even moderately complex vapor mixtures requires coupling the microsensor array to an upstream GC separation stage. For detecting low analyte concentrations, preconcentration may also be required, particularly for.. >> more

bulletPreconcentration Materials and Devices.

For preconcentration, various adsorbent materials are being developed, including carbon molecular sieves, graphitized carbons, and carbon nanotubes, with judiciously designed or selected surface areas, pore-size distributions, and/or functionalities for use in multi-stage preconcentator devices. Our collaborators in electrical and mechanical engineering are building such microfabricated devices with.. >> more

bulletSeparation Technology.

For separation of complex mixture components, we employ chromatographic separation channels etched into small Si chips. Among the most critical factors affecting the performance of such channels used as gas chromatographic (GC) separation microcolumns are the consistency and uniformity of stationary phase deposition, deactivation of surface-adsorption sites on the microcolumn walls, and the stability.. >> more

bulletChemometrics.

bulletApplications.

Indoor air quality, breath biomarker analysis, homeland security, environmental tobacco smoke, industrial hygiene.

bulletPublications.