Environmental Health Sciences
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>> Inflammatory responses of human gestational membranesThe objectives are to determine the mechanisms and downstream consequences of inflammatory responses in human gestational membranes exposed in vitro to environmental pollutants. |
>> Mechanisms of modification of uterine contraction by environmental chemicalsThe elucidation of mechanisms by which environmental chemicals modify uterine contractility using uterine smooth muscle cell cultures and and rat uterine strips suspended in muscle baths. |
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>> Environmental Agents and Reproductive Health (EARtH)With collaborators at Harvard School of Public Health, we are investigating the relationship between PCBs, phthalates, pesticides, and other agents and reproductive health in adult men. |
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>> University of Michigan Dioxin Exposure StudyCross-sectional study to determine whether Michigan residents living on or near soils contaminated with dioxins, furans and PCBs experience increased exposure. |
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>> Air-water Exchange Over Lake and Ocean Surfaces (AEOLOS)Investigating chemical exchange processes at the air-water interface. |
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>> In vitro biomarker platforms to rapidly assess the neurotoxicity of priority and emerging chemicalsThousands of different chemicals are released into our environment but few risk assessment tools are available to rapidly assess their potential to cause harm. Based on the premise that neurochemical changes precede overt neurotoxicity, our main objective is: to develop, validate, and use a practical in vitro/in vivo biomarker platform to screen the early effects of high-priority emerging contaminants.. >> more |
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>> Multiscale Multimedia source to intake modelingCreation of an adaptive multimedia model determining intake fractions at local (1km grid around the emission source), regional (200km grid within the continent of emission) and continental (world divided in continents) levels. Special emphasis is given to further develop modeling of exposure in the food chain linked to highest intake fractions and high level of uncertainties. This research builds up.. >> more |
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>> PBPK modeling to support the statistical analysis of the University of Michigan Dioxin Exposure StudyThis project develops a combined intake and physiologically based pharmacokinetic (PBPK) model to complement the regression model of the University of Michigan Dioxin Exposure Study (http://www.sph.umich.edu/dioxin/) and establish causal relationships. This work constitutes an important step in refining and building confidence in the statistical model. It will increase the model's ability to inform.. >> more |
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>> Batterman Lab - Exposure and Environmental Impact AssessmentLeader: Stuart Batterman (Ph.D.)
Our teaching and research address a wide range of topics in occupational, indoor and environmental settings. Topics include exposure assessment (especially for particulate matter and volatile organic compounds or VOCs); emerging contaminants in occupational, ecological and environmental settings (e.g., brominated flame retardants); biological monitoring (e.g., blood, breath); air quality monitoring.. >> more |
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>> Garabrant Lab - Occupational and Environmental Epidemiology (Emeritus Faculty)Leader: David H. Garabrant (M.D., M.P.H.)
Professor Garabrant is a physician who has conducted research in occupational and environmental epidemiology for the past 25 years. He is board certified in internal medicine, occupational medicine, and preventive medicine. Since joining the faculty at the University of Michigan in 1988, he has served as Director of the Occupational Medicine Program, Director of the Occupational Health Program, Director.. >> more |
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>> Harris Lab - Developmental ToxicologyLeader: Craig Harris (Ph.D.)
Welcome to the laboratory research website of Dr. Craig Harris in the Department of Environmental Health Sciences, School of Public Health, at the University of Michigan. The broad area of research interest in our laboratory involves studies to elucidate mechanisms of developmental toxicity and the mechanisms of developmental growth and differentiation that are controlled through redox.. >> more |
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>> Meeker Lab - Exposure Science; Environmental and Reproductive EpidemiologyLeader: John Meeker (Sc.D., C.I.H.)
There is growing evidence and concern that reproductive and developmental health is impacted by our surrounding environment. Well-designed, hypothesis-based human studies are greatly needed to explore these relationships and inform risk reduction strategies. Exposure assessment is a vital component in environmental epidemiologic studies, yet the details of measuring exposure and the appropriateness.. >> more |
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>> Loch-Caruso Lab - Pollutants and ParturitionLeader: Rita Loch-Caruso (Ph.D.)
The Loch-Caruso Lab is interested in toxicants as potential risks for normal and timely childbirth. Working with cell, tissue and animal experimental models, our work focuses on mechanisms by which environmental chemical exposures modify cellular and physiological processess involved in parturition. Using multip-disciplinary approaches that span molecular biology to human subjects research, current.. >> more |
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