| Search for Keywords |
 |
Projects
|
Asthma is the most common chronic disease of childhood in the United States. Many important triggers of asthma, including allergens and airborne particulate matter (PM), occur in the indoor environment. This intervention is a randomized controlled trial of the efficacy of air filters (AFs) alone, and AFs together with air conditioners (ACs), to reduce indoor PM and improve health status of children.. >> more
|
 |
|
This project examines the efficacy of air particulate filtration in the home for asthmatic children in Detroit.
|
 |
|
The aims of this project are to examine the association between ambient air pollution and sub-clinical markers of cardiovascular disease (heart rate variability, cardiac function, homocysteine) and to assess genes-environment and nutrient-environment interactions.
|
|
Goal: To elucidate the underlying patho-physiological mechanisms linking air pollution with impaired arterial reactivity; to clarify the health significance of air pollution-mediated arterial vasoconstriction.
|
 |
|
Goal: To study the effect of PM2.5 pre-exposure on blood pressure and vascular function following angiotensin II infusion; and to investigate the role of vasoconstrictor mechanisms activated by ROS in response to PM2.5 pre-exposure.
|
 |
|
Investigating chemical exchange processes at the air-water interface.
|
 |
|
This project has developed a multi-media training material (combining text, animation, pictures, and audio-visuals) on indoor air quality and asthma. The modules include the risk factors for asthma, a virtual home showing locations of asthma triggers, resource guide, and a home assessment tool. Questions are included at the end of some modules to test the grasp of material covered. A large report.. >> more
|
 |
|
Goal: To develop a PM2.5 extraction protocol suitable for in vitro mechanistic studies; to develop an in vitro assay of PM2.5 effect on respiratory epithelial cells; to determine variation in epithelial cellular responses by PM composition profile using sample filters collected at different geographic locations representing 8 different mixtures of PM2.5 emission sources and investigate interactive.. >> more
|
 |
|
This study will develop and evaluate a direct health indicator of pediatric asthma morbidity resulting from exposure to ambient air pollutants using an epidemiological approach that merges existing datasets and incorporates population susceptibility, exposure patterns, and other local conditions.
|
 |
|
This research characterizes the distributions and determinants of air pollutant exposures of volatile organic compounds (VOCs) in representative urban populations along an urban/industrial gradient, and investigates microenvironments and other factors affecting exposures
|
 |
|
This research aims to better understand the distribution of mobile BFRs in residential, commercial and industrial buildings and to estimate emissions from urban sources into ambient air that may ultimately be deposited into the Great Lakes region
|
 |
|
This research aims to better understand the emissions of PBDEs from residential buildings and to estimate emissions from urban sources into ambient air that may ultimately be deposited into the Great Lakes region
|
 |
|
This grant sponsors students, research, training and faculty exchange for personnel in southern African in academic, governmental and labor organizations addressing environmental and industrial health issues
|
 |
|
The goals of this project are to characterize the distribution of exposures to volatile organic compounds (VOCs) measured as part of the National Health and Nutrition Examination Survey (NHANES) population.
|
 |
|
This project examines the relationship between ambient and indoor exposure to diesel exhaust and other air pollutants and the response of children with asthma living in the Detroit area.
|
 |
|
This partnership between UM and Centre for Environmental Chemistry in Obninsk, Russia will address the migration and impacts of persistent organic pollutants in the Arctic region.
|
 |
|
This work considers a new class of materials known as engineered cementitious composites (ECC) that can enhance the sustainability of bridge, road and pipe infrastructure. It explores impacts on sustainability performance of concrete replacement with ECC, material sourcing alternatives (e.g., superquarries vs. smaller mines), and location of infrastructure projects (e.g., urban vs. rural, and U.S... >> more
|
 |
|
The objectives of this study are to (1) determine the health status of the Durban South residents, with specific reference to respiratory health outcomes and other chronic diseases and to determine the relationship between environmental pollution, these health outcomes and the quality of life within this community, particularly among susceptible populations, and (2) to describe the range of ambient.. >> more
|
 |
|
Goal: To address the recommendations to States by USEPA regarding Mercury Reduction Programs, including: 1) identification of the potential air emission sources or source categories contributing to local and regional atmospheric mercury deposition, as well as, 2) the support of long-term atmospheric mercury monitoring networks, in Michigan.
|
 |
|
The Collaborative Air Research Effort is a joint interdisciplinary program between the Michigan State Universtiy and the University of Michigan investigating the health effects of air pollutants.
|
 |
|
In this study we are utilizing questionnaire data and multiple biological exposure estimates among couples undergoing assisted reproduction to investigate associations between secondhand tobacco smoke exposure and female fertility, embryo development, and adverse birth outcomes.
|
 |
|
Creation of an adaptive multimedia model determining intake fractions at local (1km grid around the emission source), regional (200km grid within the continent of emission) and continental (world divided in continents) levels. Special emphasis is given to further develop modeling of exposure in the food chain linked to highest intake fractions and high level of uncertainties. This research builds up.. >> more
|
 |
|
We aim to estimate global health impacts of trade by linking three actors: the producers of goods, the consumers of the goods, and the population impacted by the pollution (producers, consumers or a third party). Exchanges through trade (embodied pollution content) and multi-media pollutant transfer are considered on a global scale.
|
 |
|
The major goal is to use environmental survey, laboratory experimental study and mathematic modeling to investigate the role of free DNA and biofilms in the spread of antibiotic resistance in surface water and drinking water.
|
 |
|
This project seeks to specify the optimal quantities and types of high-surface-area adsorbent materials for the u-preconcentrator/focuser (uPCF) module of the WIMS uGC, and to define the optimal operating conditions for the uPCF.
|
 |
|
Developing the analytical and measurement techniques necessary to estimate the atmospheric loading of mercury to sensitive, aquatic ecosystems.
|
 |
|
The "South End" neighborhood in Dearborn, one of the most polluted areas of Michigan, serves as an immigrant reception area for a low-income, predominantly Arab American population. The focus of this study is to assess the exposures of the Arab American population, especially in this area, to environmental contaminants in their home and neighborhood. Specific aims of the project include: (I). Create.. >> more
|
 |
|
This research program takes a holistic approach to understanding the sources and cycling of mercury in the Lake Superior Basin.
|
 |
|
In June of 2004, we established a new Center for Children's Environmental Health and Disease Prevention Research with support from the U.S. Environmental Protection Agency and the National Institute for Environmental Health Sciences. Our Center addresses the concerns of a community living in the Tar Creek Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese,.. >> more
|
 |
|
In most applications of microfabricated sensor arrays to multi-vapor analysis, the devices employed operate on the same transduction principle. It stands to reason that arrays incorporating sensors that operate on different transduction principles should enhance response diversity by probing different aspects of the vapor-interface interaction and, thereby, improve vapor discrimination. This study.. >> more
|
 |
|
In this project we are exploring alternative detectors for the WIMS uGC that consist of arrays microsensors that operate on different transduction principles. Chemiresistors (CR), thickness-shear mode resonators (TSMR) and film bulk acoustic resonators (FBAR) are being studied. Each is coated with a film of a functionalized thiolate-monolayer-protected gold nanoparticle (MPN), which serves as the.. >> more
|
 |
|
This project develops a combined intake and physiologically based pharmacokinetic (PBPK) model to complement the regression model of the University of Michigan Dioxin Exposure Study (http://www.sph.umich.edu/dioxin/) and establish causal relationships. This work constitutes an important step in refining and building confidence in the statistical model. It will increase the model's ability to inform.. >> more
|
 |
|
Environmental tobacco smoke (ETS) is a complex mixture of compounds collectively classified by the International Agency for Research on Cancer as a carcinogenic substance. The complexity of ETS and the presence of confounding sources of some ETS constituents in many environments have impeded accurate exposure assessments and have led to efforts to find surrogate measures of ETS contamination levels... >> more
|
 |
|
The aims of this projects are to assess the consistency of chromatographic resolution achievable from multiple microfabricated glass/Si separation columns statically coated with non-polar and polar stationary phases, to develop better polar and non-polar techniquies with surface pre-treatment methods and to evaluate the effect of thermal cycling on an air matrix. A series of 3-meter and 1-meter columns.. >> more
|
 |
|
Among the most critical factors affecting the performance of the WIMS uGC relate to the DRIE-Si/glass channels used as gas chromatographic (GC) separation microcolumns, specifically, the consistency and uniformity of stationary phase deposition, deactivation of surface-adsorption sites on the microcolumn walls, and the stability of the stationary phase following repeated thermal cycling. This year,.. >> more
|
 |
|
The burden of childhood asthma disproportionately affects children living in poverty and in urban centers, many of whom are minority ethnic groups. For those living in urban environments with high traffic densities, there is increasing concern about potential adverse respiratory health effects of exposure to diesel and other vehicular exhaust. Epidemiologic studies have shown associations between.. >> more
|
 |
|
This project aims to explore and better understand the source-to-body fate, exposure and body distribution of polybrominated diphenyl ethers (PBDEs) and PAHs. PBDEs are considered emerging contaminants of great concern due to both their toxicity and the rapidly rising levels found in human and in the environment. The idea is to couple multimedia fate and exposure models with physiologically-based pharmacokinetic.. >> more
|
|
Antibiotic resistance is known to spread through person-to-person contact, but an environmental route of transmission may also be important in the current surge in antibiotic resistant infections. By mathematically modeling a person-environment-person pathway, we will provide insight into how antibiotic resistance emerges and is transported through the environment.
|
 |
|
The Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) Project is a group of epidemiologic birth cohort studies with the mission of investigating the influence of environmental toxicant exposures on the development and future health of the fetus and infant.
|
 |
|
The Normative Aging Study (NAS) is a longitudinal study of 2,280 healthy male volunteers begun in Boston in the 1960s. Beginning in 1991 with an NIEHS R01 grant to study the impact of environmental lead exposure on risk of hypertension (NIEHS R01 ES 05257; PI: Howard Hu), NAS participants were invited to undergo bone and blood lead measurements. This project and a series of successful competitive.. >> more
|
|
Our group conducted this study, the first ever to investigate associations between exposures to common ambient air pollutants and respiratory health status conducted among children in the South Durban industrial basin.
|
 |
|
This study is investigating associations between exposures to common ambient air pollutants and respiratory health status (symptom prevalences and pulmonary function measures) in children living in both industrialized and non-industrialized areas of a large metropolitan city in South Africa. The South Durban Industrial Basin is a residential-industrial complex which arose during an era of racist (apartheid).. >> more
|
 |
|
The University of Michigan Center for Occupational Health and Safety Engineering (COHSE), a NIOSH-funded Education and Research Center (ERC), provides comprehensive professional and research training in Industrial Hygiene (IH), Occupational Health Nursing (OHN), Occupational Safety Engineering and Ergonomics (OSE), Hazardous Substances Academic Training (HSAT), Occupational Epidemiology (OE), and Pilot.. >> more
|
 |
|
Chemiresistor (CR) sensor arrays employing thiolate-monolayer-protected gold nanoparticles (MPNs) as interfacial films are being developed for the selective detection of explosives and tagants. Hexafluoro-alcohol functionalized MPNs (HFA-MPNs) are being incorporated into CR arrays because of their affinity for the nitro-aromatic functionality present in many explosives. Composite films of HFA-MPNs.. >> more
|
 |
|
Our group has been continually funded by the Fogarty International Center since 1996 to strengthen capacity through training and research in Environmental and Occupational Health (EOH) in the 14-nation Southern Africa Development Community (SADC) region. The major strategy for sustainable capacity building is to leverage regional strengths in South Africa to support the development of academic research.. >> more
|
 |
|
Using the UNEP-SETAC toxicity model (USEtox), this project aims to recommended and interim characterisation factors for human health and freshwater ecotoxicity impacts. These developments that are essential for an improved comparative assessment of chemicals is carried out in direct collaboration with the model developers of CalTOX, IMPACT 2002, USES-LCA, BETR and EDIP.
|
 |
Groups
|
Leader: Gerald Keeler (Ph.D.)
The Air Quality Laboratory (AQL) presents a unique interdisciplinary approach to solving complex environmental problems, and for investigating fundamental scientific questions and processes. Research interests include the measurement and modeling of hazardous air pollutants (HAPs), air pollution meteorology, whole ecosystem studies of the cycling of trace elements in the environment.
|
 |
|
Leader: Sung Kyun Park (Sc.D., M.P.H.)
Sung Kyun is interested in health effects of air pollution and metals exposure in aging populations. He has been working on the associations between air pollution, lead and subclinical cardiovascular outcomes, such as heart rate variability and homocysteine, using the Normative Aging Study. Sung Kyun is working on age-related diseases, such as impairment in renal function, age-related cataract and.. >> more
|
 |
|
Leader: J. Timothy Dvonch (Ph.D.)
Dr. Dvonch's work focuses on the exposure assessment, source identification, and health effects of air pollutants. He obtained a B.S. in Chemistry in 1992. In 1994, he earned an M.S. in Environmental Health Sciences, and subsequently a Ph.D. in Environmental Health Sciences in 1998. Dr. Dvonch collaborates on several large multi-disciplinary projects focused on environmental exposures and their related.. >> more
|
 |
|
Leader: Thomas Robins (M.D., M.P.H.)
Our research, teaching and service address a wide range of issues in environmental and occupational health, both in Southern Africa and in United States. Most of our research studies involve primary exposure and health status data collection and characterization in large-scale longitudinal field studies. In our approach to research we emphasize community-based participatory methods, capacity strengthening,.. >> more
|
 |
|
Leader: Marie S. O'Neill (Ph.D.)
Our research in environmental epidemiology addresses associations between air pollution and health, climate change and health (with a specific emphasis on extreme temperatures) and environmental equity. Most research is accomplished using secondary datasets, including vital statistics data based in the U.S. and Latin America (Mexico, Chile and Brazil); data from large epidemiologic cohorts (Normative.. >> more
|
 |
|
Leader: Stuart Batterman (Ph.D.)
Our teaching and research address a wide range of topics in occupational, indoor and environmental settings. Topics include exposure assessment (especially for particulate matter and volatile organic compounds or VOCs); emerging contaminants in occupational, ecological and environmental settings (e.g., brominated flame retardants); biological monitoring (e.g., blood, breath); air quality monitoring.. >> more
|
 |
|
Leader: Edward T. Zellers (Ph.D.)
The assessment of human exposure to complex mixtures of natural and anthropogenic chemicals ranks among the most important global environmental health challenges. Our ability to meet evolving needs in this area relies critically on innovations in exposure science and technology. Advances that facilitate accurate, high-resolution measurements are integral to mankind's efforts to unravel the intricate.. >> more
|
 |
|
Leader: Peter Mancuso (Ph.D.)
Peter Mancuso is an interdisciplinary scientist whose research focuses on environmental factors that regulate pulmonary immune responses. He has used cellular, molecular and integrative biology to determine the impact of environmental influences such as obesity, malnutrition, and tobacco smoke exposure on alveolar macrophage and pulmonary innate immune responses to bacterial infection. He is a member.. >> more
|
 |
|
Leader: Jerome Nriagu (Ph.D., D.Sc.)
Prof. Nriagu's research and teaching programs center around three main issues: (i) sources, behavior, fate and effects of metals in the natural and contaminated environments; (ii) environmental justice and disproportionate exposure of communities to environmental pollutants; and (iii) environmental health problems in the developing countries. His work includes applied laboratory and field studies and.. >> more
|
 |
People from SPH
