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Projects
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This project examines the efficacy of air particulate filtration in the home for asthmatic children in Detroit.
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Exposure to metals, particularly lead, has been associated with the development of PD in a few but highly-suggestive studies. This topic has not yet been studied epidemiologically using state-of-the-art biological marker techniques for measuring metals exposure and accumulation.
Our research team has taken advantage of well-described, highly motivated and geographically convenient populations of PD.. >> more
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In June of 2004, we established a new Center for Children's Environmental Health and Disease Prevention Research with support from the U.S. Environmental Protection Agency and the National Institute for Environmental Health Sciences. Our Center addresses the concerns of a community living in the Tar Creek Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese,.. >> more
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The goals of this project are to characterize the distribution of exposures to volatile organic compounds (VOCs) measured as part of the National Health and Nutrition Examination Survey (NHANES) population.
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This project examines the relationship between ambient and indoor exposure to diesel exhaust and other air pollutants and the response of children with asthma living in the Detroit area.
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This study will develop and evaluate a direct health indicator of pediatric asthma morbidity resulting from exposure to ambient air pollutants using an epidemiological approach that merges existing datasets and incorporates population susceptibility, exposure patterns, and other local conditions.
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The Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) Project is a group of epidemiologic birth cohort studies with the mission of investigating the influence of environmental toxicant exposures on the development and future health of the fetus and infant.
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The Normative Aging Study (NAS) is a longitudinal study of 2,280 healthy male volunteers begun in Boston in the 1960s. Beginning in 1991 with an NIEHS R01 grant to study the impact of environmental lead exposure on risk of hypertension (NIEHS R01 ES 05257; PI: Howard Hu), NAS participants were invited to undergo bone and blood lead measurements. This project and a series of successful competitive.. >> more
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The objectives of this study are to (1) determine the health status of the Durban South residents, with specific reference to respiratory health outcomes and other chronic diseases and to determine the relationship between environmental pollution, these health outcomes and the quality of life within this community, particularly among susceptible populations, and (2) to describe the range of ambient.. >> more
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Lead exposure poses a major environmental health problem in India. No direct studies have yet been performed in India to investigate the impact of lead exposure on outcomes such as neurobehavioral development. We propose to build upon a collaborative effort initiated during the proposed PI's work as a Senior Fulbright Scholar and work with colleagues at the Sri Ramachandra Medical College and Research.. >> more
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Goal: To provide insight into toxicological mechanisms of PM-induced cardiopulmonary effects, particularly as they relate to susceptible subpopulations; and generate toxicological data to directly correspond to epidemiology and exposure assessment data from concurrent studies being conducted at one of the project locations.
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The health risks associated with long-term exposure to arsenic in drinking are still not well understood. Our research deals with the effects of arseninc exposure at elevated (in MIchigan) and high (Nadia Province, West Bengal, India) levels. The primary goal of the Michigan is to assess the effects of exposure to elevated levels of arsenic in drinking water as a risk factor in the development of.. >> more
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The University of Michigan Center for Occupational Health and Safety Engineering (COHSE), a NIOSH-funded Education and Research Center (ERC), provides comprehensive professional and research training in Industrial Hygiene (IH), Occupational Health Nursing (OHN), Occupational Safety Engineering and Ergonomics (OSE), Hazardous Substances Academic Training (HSAT), Occupational Epidemiology (OE), and Pilot.. >> more
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Groups
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Leader: Thomas Robins (M.D., M.P.H.)
Our research, teaching and service address a wide range of issues in environmental and occupational health, both in Southern Africa and in United States. Most of our research studies involve primary exposure and health status data collection and characterization in large-scale longitudinal field studies. In our approach to research we emphasize community-based participatory methods, capacity strengthening,.. >> more
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Leader: Marie S. O'Neill (Ph.D.)
Our research in environmental epidemiology addresses associations between air pollution and health, climate change and health (with a specific emphasis on extreme temperatures) and environmental equity. Most research is accomplished using secondary datasets, including vital statistics data based in the U.S. and Latin America (Mexico, Chile and Brazil); data from large epidemiologic cohorts (Normative.. >> more
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Leader: Sung Kyun Park (Sc.D., M.P.H.)
Sung Kyun is interested in health effects of air pollution and metals exposure in aging populations. He has been working on the associations between air pollution, lead and subclinical cardiovascular outcomes, such as heart rate variability and homocysteine, using the Normative Aging Study. Sung Kyun is working on age-related diseases, such as impairment in renal function, age-related cataract and.. >> more
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Leader: John Meeker (Sc.D., C.I.H.)
There is growing evidence and concern that reproductive and developmental health is impacted by our surrounding environment. Well-designed, hypothesis-based human studies are greatly needed to explore these relationships and inform risk reduction strategies. Exposure assessment is a vital component in environmental epidemiologic studies, yet the details of measuring exposure and the appropriateness.. >> more
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Leader: Howard Hu (M.D., M.P.H., Sc.D.)
The Mission of the Michigan Metals Epidemiology Research Group (MERG) is to gain new insights into the impacts of exposure to potentially toxic metals that are of critical importance to public health and medicine by applying multi-disciplinary and novel methods of exposure assessment, genetics, nutrition, psychosocial factors and clinical measurements in epidemiologic studies of human populations around.. >> more
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Leader: David H. Garabrant (M.D., M.P.H.)
Professor Garabrant is a physician who has conducted research in occupational and environmental epidemiology for the past 25 years. He is board certified in internal medicine, occupational medicine, and preventive medicine. Since joining the faculty at the University of Michigan in 1988, he has served as Director of the Occupational Medicine Program, Director of the Occupational Health Program, Director.. >> more
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Leader: Stuart Batterman (Ph.D.)
Our teaching and research address a wide range of topics in occupational, indoor and environmental settings. Topics include exposure assessment (especially for particulate matter and volatile organic compounds or VOCs); emerging contaminants in occupational, ecological and environmental settings (e.g., brominated flame retardants); biological monitoring (e.g., blood, breath); air quality monitoring.. >> more
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Leader: Rudy Richardson (Sc.D., D.A.B.T.)
The Richardson lab is concerned with understanding mechanisms of neurodegeneration or vascular disease mediated by age, genetics, and exposures to environmental agents. Knowledge gained about mechanisms is used to develop biomarkers or biosensors of exposure or disease and to enhance the process of risk assessment. We focus on examining interactions of small molecules with target proteins using kinetics.. >> more
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People from SPH
